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Ago 05, 2022

PICCs and CICCs in the management of septic shock patients in the ICU

Peripherally inserted central catheters (PICCs) are increasingly recognized as an alternative to centrally inserted central catheters (CICCs) in critical care.

However, the data regarding the safety and feasibility of this choice in septic shock management is growing but still lacking.

A recent study1 aimed to determine the feasibility, safety, and impact on outcomes of using dedicated vascular access specialist teams to insert PICCs versus CICCs on patients admitted to the ICU with septic shock. Let's see the results.

PICC and CICC in patients with septic shock in the intensive care unit: study results

A total of 562 patients with septic shock were included in the study: 215 of these were resuscitated utilizing a PICC and 347 were resuscitated using a CICC.

On univariate analysis, the time to central line insertion and time to vasopressor initiation were found to be reduced in those who received PICC at time of ICU admission versus CICC. Other favorable outcomes were also observed in those who received PICC versus CICC, including:

  • shorter ICU length of stay;
  • lower unadjusted hospital mortality.

A multivariable analysis for hospital mortality showed that after adjusting for important covariates, neither the time to central line insertion nor the time to vasopressor initiation was associated with a lower hospital mortality.

The conclusions of the study point out that across two tertiary referral centers within the same enterprise, use of a dedicated VAS team for insertion of PICCs for initial resuscitation in patients with septic shock was feasible and associated with shorter time to central venous access and initiation of vasopressors. However, adjusted hospital mortality was not different between the two groups.

Delta Med PICCs, for effective and safe procedures

Delta Med designs and manufactures state-of-the-art polyurethane PICCs, available in different sizes, configurations, and gauges (single lumen, bilumen or trilumen).

The devices in the PICC range have all the features to ensure implantation of the device in the utmost safety of patients and healthcare professionals. In addition, they ensure:

  • infusion with high-pressure therapies (300 PSI) for long periods;
  • reduced primary and secondary complications;
  • high biocompatibility and biostability.

Delta Med PICCs can be placed with ECG technique (the composition with ECG cable and device is available in all our sets).

Want more information about our catheters and different possible solutions? Contact us today, without obligation, to speak with one of our professionals.



1 Use of peripherally inserted central catheters with a dedicated vascular access specialists team versus centrally inserted central catheters in the management of septic shock patients in the ICU, Hassan A Raza, Brandon T Nokes, Bruno Alvarez, Julie Colquist, John Park, Rahul Kashyap, Bhavesh Patel, Rodrigo Cartin-Ceba.

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